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− | {{Vilnius-Lithuania/TopBar}}
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− | <link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/index.css&action=raw&ctype=text/css" />
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− | </head>
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− | <body>
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− | <section class="container" id="intro-page">
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− | <div id="intro-header">
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− | <path id="wave0" d="" fill="#fafafc" waveHeight="360" waveDelta="30" speed="0.2" wavePoints="8" />
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− | </svg>
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− | </div>
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− | <div id="intro">
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− | <div id="text-wrapper">
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− | <div id="title">
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− | <h1>flavoflow</h1>
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− | </div>
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− | <div id="desc-wrapper">
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− | <div id="center-desc" style="width: -webkit-fit-content;">
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− | <span id="description"></span>
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− | </div>
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− | </div>
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− | </div>
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− | </div>
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− | <div id="bubbles-container">
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− | </div>
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− | </section>
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− | <main id="storytelling">
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− | <div class="black-bg big-section">
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− | <div id="firstpart" class="section centered">
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− | <div id="fish-icon" class="centered icon white">
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− | <p class="black center">Throughout history <b>fish</b> have always been one of the most <b>important food sources.</b></p>
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− | </div>
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− | </div>
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− | <div id="secondpart" class="section centered">
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− | <div class="centered wdt-60">
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− | <p class="white center">The consumption of aquaculture products has been steadily increasing during the past <b>50 years</b> and has now <b>doubled</b> since.</p>
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− | <div class="icon dark"></div>
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− | </div>
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− | <div id="thirdpart" class="section centered">
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− | <div class="half">
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− | <p class="white">Growing fish consumption drives a need for a more <b>intensive fish farming</b> - a need which emerging aquaculture farms have stepped in to satisfy.</p>
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− | </div>
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− | <div class="icon dark"></div>
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− | </div>
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− | </div>
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− | <div id="fourthpart" class="section centered">
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− | <div class="half">
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− | <p class="white">In order to obtain greater amounts of fish in a shorter period of time, aquafarms have implemented <b>recirculating aquaculture systems</b> (RAS).</p>
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− | </div>
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− | <div class="half">
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− | <div class="icon dark"></div>
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− | <div id="fifthpart" class="section">
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− | <div class="half">
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− | <h2 class="white">Advantages of RAS</h2>
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− | <div class="list">
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− | <div class="list-item">
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− | <div></div>
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− | <p class="center">reduced water and land needs</p>
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− | </div>
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− | <div class="list-item">
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− | <div></div>
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− | <p class="center">fully controlled environment</p>
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− | </div>
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− | <div class="list-item">
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− | <div></div>
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− | <p class="center">automated feeding strategy</p>
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− | </div>
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− | </div>
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− | <div class="half">
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− | <h2 class="white">Disadvantages of RAS</h2>
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− | <div class="list">
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− | <div class="list-item">
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− | <div></div>
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− | <p class="center">high electricity consumption</p>
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− | </div>
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− | <div class="list-item">
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− | <div></div>
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− | <p class="center">water quality</p>
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− | </div>
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− | </div>
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− | </div>
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− | </div>
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− | <div id="sixthpart" class="section centered">
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− | <div class="centered">
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− | <h1>However, the biggest challenge is</p>
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− | <div id="seventhpart" class="section centered">
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− | <div class="half">
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− | <p class="white">Since the water in RAS is circulated between tanks, if <b>one bacteria-infected fish</b> enters the system, not long after, the entire RAS system can become <b>contaminated</b>.</p>
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− | </div>
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− | </div>
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− | </div>
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− | <!--
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− | <div class="white-bg big-section">
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− | <div class="section centered wdt-60">
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− | <div>
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− | <p class="black center">Diseases caused by Flavobacterium spp. constitute one of the <b>biggest host</b> and geographic ranges of the <b>bacterial fish pathogens</b>.</p>
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− | </div>
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− | </div>
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− | <div id="bact" class="section centered">
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− | <div>
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− | <p class="black center">The<b> most common</b> of these bacteria are the two opportunistic species:</p>
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− | </div>
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− | <div class="row">
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− | <p class="black center">Flavobacterium<br>psychrophilum</p>
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− | <p class="yellow center"><b>causes bacterial gill disease</b></p>
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− | </div>
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− | <div class="half">
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− | <p class="black center">Flavobacterium<br>columnare</p>
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− | <p class="yellow center"><b>causes columnaris disease</b></p>
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− | </div>
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− | </div>
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− | </div>
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− | </div>
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− | <div class="black-bg big-section">
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− | <div class="section centered">
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− | <div class="centered">
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− | <h1>What's the deal with the fish?</p>
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− | </div>
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− | </div>
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− | <div id="fish-symptoms" class="section centered wdt-80">
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− | <div class="half">
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− | <p class="white">Typically, these diseases are denoted by heavy bacterial colonizations of gill epithelium and eroded fin tips.</p>
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− | <p class="white">However, after these physical changes are being seen, the respiratory and osmoregulatory functions are already damaged.</p>
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− | <p class="white">Thus, if the disease is not detected in a span of a few days, it can result in massive fish die-offs.</p>
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− | </div>
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− | <div class="half">
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− | <div class="icon dark"></div>
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− | </div>
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− | </div>
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− | <div class="section centered">
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− | <div class="centered">
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− | <h2 class="white">Are there any solutions to this problem?</h2>
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− | </div>
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− | </div>
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− | </div>
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− | <div class="white-bg big-section">
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− | <div class="section centered wdt-60">
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− | <div class="centered">
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− | <h1 class="black center">Actually, yes!</h1>
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− | </div>
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− | </div>
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− | <div class="section centered wdt-60">
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− | <p class="black center">We have found <b>three</b> major approaches to solving the Flavoproblem.</p>
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− | </div>
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− | </div>
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− | </div>
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− | <div class="lightblue-bg big-section">
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− | <div class="section centered">
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− | <div class="centered">
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− | <h1 class="white title">detection</h1>
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− | </div>
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− | </div>
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− | <div class="section centered wd-50">
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− | <div>
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− | <p class="white">One of our main goals is the development of a rapid detection test is based on helicase-dependent amplification (HDA) and lateral-flow assay (LFA) methods. This kit will help farmers in identifying what the Flavo is in their tanks.</p>
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− | </div>
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− | </div>
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− | <div class="section centered wd-50">
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− | <div>
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− | <p class="white">Detection, however, is only a tool which will reduce aquafarm’s losses - it will not solve the underlying problem.</p>
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− | </div>
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− | </div>
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− | </div>
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− | <div class="brightblue-bg big-section">
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− | <div class="section centered">
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− | <div class="centered">
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− | <h1 class="white title">treatment</h1>
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− | </div>
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− | </div>
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− | <div class="section centered wd-50">
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− | <div>
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− | <p class="white">Due to this reason, we have developed a new fundamental method to treat these diseases based on toxin-antitoxin or exolysin-endolysin systems. </p>
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− | <p class="white">On the other hand, no matter how perfect the treatment strategy is, it solves only the consequences of the disease.</p>
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− | </div>
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− | </div>
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− | </div>
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− | <div class="darkblue-bg big-section">
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− | <div class="section centered">
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− | <div class="centered">
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− | <h1 class="white title">prevention</h1>
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− | </div>
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− | </div>
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− | <div class="section centered wd-50">
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− | <div>
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− | <p class="white">Keeping this in mind, we have also created an innovative prevention tool, which is based on the packaging of immunogenic proteins into alginate beads. </p>
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− | </div>
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− | </div>
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− | </div>
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− | <div id="links" class="black-bg big-section">
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− | <div class="section centered">
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− | <div class="centered">
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− | <h1 class="white title">let's dive in</h1>
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− | </div>
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− | </div>
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− | <div class="section centered nf">
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