Difference between revisions of "Team:Paris Bettencourt/Implementation"
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| − | <area shape="circle" coords="968,108,78" alt="Quaranskin" href="https://2020.igem.org/Team:Paris_Bettencourt/ | + | <area shape="circle" coords="968,108,78" alt="Quaranskin" href="https://2020.igem.org/Team:Paris_Bettencourt/Human_Practices"> |
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<area shape="circle" coords="1322,248,78" alt="Epi Grow" href="https://2020.igem.org/Team:Paris_Bettencourt/Project/EpiGrow"> | <area shape="circle" coords="1322,248,78" alt="Epi Grow" href="https://2020.igem.org/Team:Paris_Bettencourt/Project/EpiGrow"> | ||
<area shape="circle" coords="1279,452,78" alt="Epi Glow" href="https://2020.igem.org/Team:Paris_Bettencourt/Project/EpiGlow"> | <area shape="circle" coords="1279,452,78" alt="Epi Glow" href="https://2020.igem.org/Team:Paris_Bettencourt/Project/EpiGlow"> | ||
</map> | </map> | ||
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| + | <div class="container"> | ||
| + | <div class="row"> | ||
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| + | <h3>Implementation</h3> | ||
| + | <p>By setting up the Quaranskin project, we had to read literature on Skin Microbiome and also meet experts in the field. Some discussions with dermatologists during confinement increased our interest in the therapeutic application of synthetic biology to cure skin disorder. Also, we learned that in this context of a pandemic the fact that we need to wash more ofter our hand is a real problem for people who present symptoms of eczema. You can find more information about these discussions on the <a href="https://2020.igem.org/Team:Paris_Bettencourt/Human_Practices">Human Practices page</a>. From this point we decided to develop the SynDerma project which aims to engineer <i>S.epidermidis</i>, a commensal bacteria of the skin microbiome to control the population growth of pathogenic bacteria, such as <i>S. aureus</i> which, when overgrown, is a factor of eczema. Since no synthetic biology tools were developed to engineer <i>S. epidermidis</i>, we decided to develop a MoClo toolkit, EpiFlex, and a project of growth and electroporation protocol optimization.</p> | ||
| + | </div> | ||
| + | </div> | ||
| + | </div> | ||
<footer class="page-footer"> | <footer class="page-footer"> | ||
Revision as of 22:29, 25 October 2020
Implementation
By setting up the Quaranskin project, we had to read literature on Skin Microbiome and also meet experts in the field. Some discussions with dermatologists during confinement increased our interest in the therapeutic application of synthetic biology to cure skin disorder. Also, we learned that in this context of a pandemic the fact that we need to wash more ofter our hand is a real problem for people who present symptoms of eczema. You can find more information about these discussions on the Human Practices page. From this point we decided to develop the SynDerma project which aims to engineer S.epidermidis, a commensal bacteria of the skin microbiome to control the population growth of pathogenic bacteria, such as S. aureus which, when overgrown, is a factor of eczema. Since no synthetic biology tools were developed to engineer S. epidermidis, we decided to develop a MoClo toolkit, EpiFlex, and a project of growth and electroporation protocol optimization.