As part of our project, we submitted the fusion gene xplA/B as a biobrick in igem’s registry. This part is specific for biodegradation of the nitro-explosive 1,3,5-Trinitro-1,3,5 triazine, better known as RDX. This compound can be found in various bombs used in wars. Alongside other explosive compounds, RDX has proven to be toxic, and can cause toxic encephalopathy, convulsions, and has a possibility to contribute to cancer. In addition, toxicity to plants has also been reported. To mitigate this abundant problem, the xplA/B fusion gene has been created to fulfill the need of a biodegradable mechanism that can eliminate RDX in nature.

Currently, there are not many parts on the Registry associated with detection and biodegradation of RDX. One of the goals of iGEM RUM-UPRM is to keep expanding the Registry with parts, such as xplA/B, to help other teams detect and biodegrade RDX. In the future, we want to be able to assist other teams in their journey to help in the degradation of other heavy metals and explosives in contaminated waters and soils.