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| } | | } |
| | | |
− | #heading { | + | .heading { |
| color: #ff0000 !important; | | color: #ff0000 !important; |
| } | | } |
| | | |
− | #padding-left { | + | .padding-left { |
| padding-left: 8px; | | padding-left: 8px; |
| } | | } |
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− | #padding-right { | + | .padding-right { |
| padding-right: 8px; | | padding-right: 8px; |
| } | | } |
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| <div class="text"> | | <div class="text"> |
| <!-- <p><b>Objectives 1.</b></p> --> | | <!-- <p><b>Objectives 1.</b></p> --> |
− | <p><b id="heading">1. Sample and Sequence the Human Skin Microbiome</b></p> | + | <p><b class="heading">1. Sample and Sequence the Human Skin Microbiome</b></p> |
| <p>Our first objective, pursued as part of the Quaranskin project, is to study the impact of | | <p>Our first objective, pursued as part of the Quaranskin project, is to study the impact of |
| environmental and behavioral factors on the skin microbiome and to provide a new | | environmental and behavioral factors on the skin microbiome and to provide a new |
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| <br /> | | <br /> |
| <!-- <p><b>Objectives 2.</b></p> --> | | <!-- <p><b>Objectives 2.</b></p> --> |
− | <p><b id="heading">2. Design tools to engineer the bacterium <i>S. epidermidis</i></b></p> | + | <p><b class="heading">2. Design tools to engineer the bacterium <i>S. epidermidis</i></b></p> |
| <p>Our second objective is to make S. epidermidis an efficient synthetic biology chassis | | <p>Our second objective is to make S. epidermidis an efficient synthetic biology chassis |
| that can be used to monitor the population dynamics of the skin microbiome. This in | | that can be used to monitor the population dynamics of the skin microbiome. This in |
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| <br /> | | <br /> |
| <br /> | | <br /> |
− | <p id="padding-left">As this situation was unprecedented, we were wondering if the | + | <p class="padding-left">As this situation was unprecedented, we were wondering if the |
| lockdown could have an | | lockdown could have an |
| impact on human health and more specifically on the composition of our skin | | impact on human health and more specifically on the composition of our skin |
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| | | |
| <div class="subsection two_thirds"> | | <div class="subsection two_thirds"> |
− | <p id="padding-right">We met some dermatologists as Stéphanie Leclerc-Mercier. She | + | <p class="padding-right">We met some dermatologists as Stéphanie Leclerc-Mercier. She |
| pointed out the fact | | pointed out the fact |
| that the new sanitary measures and hygiene habits imposed by the pandemic were a | | that the new sanitary measures and hygiene habits imposed by the pandemic were a |
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| <br /> | | <br /> |
| <br /> | | <br /> |
− | <p id="padding-left">Our team personal values led us to create a project who enters in | + | <p class="padding-left">Our team personal values led us to create a project who enters in |
| the framework of | | the framework of |
| Open and Citizen Science. Especially during the lockdown which forced us to be | | Open and Citizen Science. Especially during the lockdown which forced us to be |
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| <!--Write the text explaining this section --> | | <!--Write the text explaining this section --> |
| <div class="text"> | | <div class="text"> |
− | <p><b id="heading">1. Study the Skin Microbiome</b></p> | + | <p><b class="heading">1. Study the Skin Microbiome</b></p> |
| <p>Human skin microbiome sampling is a challenge in itself since it implies reaching out to | | <p>Human skin microbiome sampling is a challenge in itself since it implies reaching out to |
| a | | a |
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| src="https://static.igem.org/mediawiki/2020/8/89/T--Paris_Bettencourt--Poster_SkinMicrobiomeStudy.png"> | | src="https://static.igem.org/mediawiki/2020/8/89/T--Paris_Bettencourt--Poster_SkinMicrobiomeStudy.png"> |
| | | |
− | <p><b id="heading">2. Engineer the Skin Microbiome</b></p> | + | <p><b class="heading">2. Engineer the Skin Microbiome</b></p> |
| <ul> | | <ul> |
| <li><i>Staphylococcus epidermidis</i> is not used in synthetic biology and no tools are | | <li><i>Staphylococcus epidermidis</i> is not used in synthetic biology and no tools are |
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| <!--Write the text explaining this section --> | | <!--Write the text explaining this section --> |
| <div class="text"> | | <div class="text"> |
− | <p><b id="heading">1. Quaranskin</b></p> | + | <p><b class="heading">1. Quaranskin</b></p> |
| <p>Quaranskin is a study involving the collection of skin microbiome samples during the | | <p>Quaranskin is a study involving the collection of skin microbiome samples during the |
| COVID-19 pandemic and | | COVID-19 pandemic and |
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| </ul> | | </ul> |
| <br /> | | <br /> |
− | <p><b id="heading">2. EpiFlex, EpiGlow, EpiGrow</b></p> | + | <p><b class="heading">2. EpiFlex, EpiGlow, EpiGrow</b></p> |
| <p>These three projects aims to develop tools to make S. epidermidis a good chassis for | | <p>These three projects aims to develop tools to make S. epidermidis a good chassis for |
| Synthetic biology. | | Synthetic biology. |
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| <div class="info"> | | <div class="info"> |
| <!--Write the title of the section --> | | <!--Write the title of the section --> |
− | <div class="title"> The Skin Microbiome</div> | + | <div class="title">The Skin Microbiome</div> |
| <!--Write the text explaining this section --> | | <!--Write the text explaining this section --> |
| <div class="text"> | | <div class="text"> |
− | <p><b id="heading">What is the Skin Microbiome?</b></p> | + | <p><b class="heading">What is the Skin Microbiome?</b></p> |
| <p>The human skin microbiome is a vast and very large ecosystem of microorganisms that | | <p>The human skin microbiome is a vast and very large ecosystem of microorganisms that |
| occupy the human skin at the level of the hypodermis, dermis, and epidermis. It is very | | occupy the human skin at the level of the hypodermis, dermis, and epidermis. It is very |
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| </p> | | </p> |
| <br /> | | <br /> |
− | <p><b id="heading">How the Skin Microbiome plays a role in the skin health?</b></p> | + | <p><b class="heading">How the Skin Microbiome plays a role in the skin health?</b></p> |
| <p>The human skin microbiome is very tightly linked to the health of its host in numerous | | <p>The human skin microbiome is very tightly linked to the health of its host in numerous |
| ways. First of all the microorganisms of the skin microbiome prevent the colonization of | | ways. First of all the microorganisms of the skin microbiome prevent the colonization of |
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| </p> | | </p> |
| <br /> | | <br /> |
− | <p><b id="heading">Why studying the composition of the Skin Microbiome?</b></p> | + | <p><b class="heading">Why studying the composition of the Skin Microbiome?</b></p> |
| <p> | | <p> |
| <ul> | | <ul> |
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| <div class="info"> | | <div class="info"> |
| <!--Write the title of the section --> | | <!--Write the title of the section --> |
− | <div class="title"> Engineering</div> | + | <div class="title">Quaranskin</div> |
| <!--Write the text explaining this section --> | | <!--Write the text explaining this section --> |
− | <div class="text"> Here you can explain the engineering process behind your project. </div> | + | <div class="text"> |
| + | <p>Quaranskin, a combination of quarantine and skin, is a project based on the collection |
| + | and analysis of skin microbiome samples, collected from participants across Europe. |
| + | </p> |
| + | <p>We aim to understand if there are correlations between behavioral characteristics that |
| + | involve activity, hygiene and human interaction, and the diversity and composition of |
| + | skin microbes at four body sites. |
| + | </p> |
| + | <img |
| + | src="https://static.igem.org/mediawiki/2020/5/5b/T--Paris_Bettencourt--Poster_Quaranskin51.jpg"> |
| + | |
| + | <p><b class="heading">Study Pipeline</b></p> |
| + | </div> |
| </div> | | </div> |
| </div> | | </div> |