Difference between revisions of "Team:Paris Bettencourt/Contribution"

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    <h5>Introduction</h5>
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    <p>Intrinsic and extrinsic factors influence the composition and distribution of the skin microbiome. The skin is always exposed to the external environment, intrinsic host factors along with extrinsic factors such as climate and habitat have a great influence on the microbial flora that colonize the skin. To effectively implement our goal of developing <i>Staphylococcus epidermidis</i> as a chassis for synthetic biology of the skin microbiome, it was essential to explore the growth of our target organism.</p>
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<p>In particular, our team chose to probe the growth kinetics of <i>Staphylococcus epidermidis</i> with respect to change in Temperature, pH and Salinity, the three parameters that we expect to fluctuate on the skin in response to different environmental or physiological cues. We reasoned that to gain such insights will be relevant to formulating a synthetic probiotic.</p>
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Revision as of 21:35, 24 October 2020

Quaranskin
Introduction

Intrinsic and extrinsic factors influence the composition and distribution of the skin microbiome. The skin is always exposed to the external environment, intrinsic host factors along with extrinsic factors such as climate and habitat have a great influence on the microbial flora that colonize the skin. To effectively implement our goal of developing Staphylococcus epidermidis as a chassis for synthetic biology of the skin microbiome, it was essential to explore the growth of our target organism.

In particular, our team chose to probe the growth kinetics of Staphylococcus epidermidis with respect to change in Temperature, pH and Salinity, the three parameters that we expect to fluctuate on the skin in response to different environmental or physiological cues. We reasoned that to gain such insights will be relevant to formulating a synthetic probiotic.