Team:BITSPilani-Goa India/Model

Model | SugarGain | iGEM BITS Goa

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Model

Overview

Mathematical models are an integral part of our project. They allow us to gain an insight into the functioning of the constructs we designed as well as enable us to predict and verify its behaviour. As we couldn't experimentally verify our claims due the COVID-19 imposed lockdown, these models form the cornerstone of our project.

We have formed a total of six models that cover various aspects of SugarGain. To provide a brief overview, they are:

  1. A model to describe our pFruB-Cra anti-invertase construct.
  2. An in silico simulation of the kill switch.
  3. An in silico model to study the interactions between invertase and anti-invertase.
  4. A model to predict the growth of bacteria in the sugarcane matrix.
  5. A model to determine the composition and optimum viscosity of our novel polymer inoculant.
  6. A model to explain the relevance of auxotrophy in our chassis.

Click on a card to be redirected to the page for the respective model.