Team:SEHS-China/Proof Of Concept

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Implementation

Our product is designed to solve allergy problems, so providing treatment and relief for allergies is the main function of our product. Our production, histamine killer, will be put into the patient’s nasal cavity. Once "on assignment," it will immediately release DAO and degrades histamine in the patient's nasal mucosa, and emit a violet scent that warns the patient to leave the place with potential allergen. The advantage of our products is that people do not need to carry medicines all the time. Because our products remain active in the patient's nasal cavity for several days before they are triggered, once the patient USES our products, they can be protected by our products for several days in the future. At the same time, because our products rely on the detection of histamine level to determine the allergy, so it can alert the patient in the early stage of allergy is happening. This way, patients can take their medication and leave the allergen site, rather than waiting until they have very severe symptoms before realizing they are allergic. People such as the elderly, children and women can use our drugs in the allergic season such as spring. You can, you don't have to worry about allergic rhinitis.

In addition to preventing the serious consequences of allergies, our products can also be used to test the freshness of food, especially seafood. Because histamine builds up in dead fish, the amount of histamine in seafood is an indicator of how fresh the fish is. When our Histamine Sensor detects Histamine, it activates the Sequence to make LacZ, a fluorescent protein. The less production of LacZ represents that the histamine content is less, and the fish is fresher. The higher the LacZ expression, the higher the histamine content, fish is not fresh. This kind of test paper can help us distinguish the freshness of the fresh food we buy and avoid food poisoning. At the same time, these test papers can quickly help food testing agencies or government health departments to conduct food safety testing. We will also continue to improve the test paper, so that its detection time shortened, more efficient operation, more suitable for daily use.

Allergy and food safety have always been issues of great concern to people. Therefore, according to our research, the social demand for these two products is very high. This proves that these two products will be used very well after they are put into the market.

Histamine is a common biological molecule, and its presence signals a lot of things. The products we have designed demonstrate mechanisms to detect and respond to histamines so they can be used for more than just allergy prevention and food testing. Rapid histamine test technology is still needed in many fields including clinical testing, veterinary medicine and Traditional Chinese medicine. Therefore, we think our products have broad prospects. SEHS-China will be very happy to see future teams joining Histamine Test research, welcome!