He has worked on developing the replicon-based immunotherapy platform.
He was also supervising the implementation of the hotspot platform pipeline to characterize hotspots of triple negative breast cancer.
He was also instructing the team to design the logic circuits and apply synthetic biology engineering principles to the original idea. Furthermore, he mentored the mathematical and structural modeling simulations.
Ahmed Mahmoud Elshewikhy
participated in
Linker optimization.
Promoter CSE optimization.
miRNA design and interaction.
IDT and twist DNA synthesis.
Epitope HLA-interaction modeling.
Aly Mahmoud Ahmed Morsy
participated in
the writing and documentation
linkers optimization.
modelin.
miRNA modeling and design.
Abdelghany Elmashad
participated in
documenting hotspot identification of TNBC neoantigens / did 3 illustrations using biorender / made a presentation on that
analyzing some NCBI datasets and grouping samples in each set then analyzing with geo2r / filtered them using logfc, t and p values to get top 10 antigen in each data set
searched for mutation in some genes then get the sequence of those different mutation to custommune to get top 3 HLA epitopes then using the consensus sequence to IEDB to get b-cell epitopes / 2 biorender illustrations
Mohamed Osama Mohamed
participated in
take over all graphic design for the team.
design the wiki.
design the poster.
Yasser Elbedewy
participated in
video editing especially (promotion video - presentation video )
saif-eldin wahba
participated in
the making of the booklet
making the survey
promotion video
designed and presented the video made for the awareness event with
our partner WIE Women INSAT organisation
made the promotion of the collaboration "Make them smile”
the documentation
Ahmed Adel Rezk
participated in
I guided the team through the Modeling and Designing steps and workflow in our project, where we worked together in the following:
1-Project Description.
2-Neo-epitope Prediction, Case Presentation and Neomutations retrieval.
3-Linker Optimization.
4-Docking Simulation.
5-Computational Validation of the antigenic epitopes and the immune response of
our proposed Vaccine versions.
6-Project Description.
7-Survey and Questionnaire design.
Ahmed Wael Mansour participated in
The development of the idea ,
Worked on phase I of selection of potential Neo-antigens and epitopes for targeting,
Worked on the design of the circuit as well as added improvements to it.
worked on adding those parts to the registry as well as finding characterization to them from literature.
helped in human practices as well as collaborations.
Supervised on selected parts optimization
Raed Ouerfelli
participated in
developed our mesmerizing wiki
Taycir Ben Ammar
participated in
the one behind the scene running all our social accounts and she participated in Human Practices activities.
