...aims to create a cellular biosensor adaptable to detect your analytes of choice. Its design contains a sensory module, where nanobodies interact with the targets, activating the signal amplification module, which will result in an output signal visible to the naked eye. Placing this system in an easy-to-use format, we intend to offer a standardized, flexible and accessible detection system. Read more here.
In the Lab
Parallelly to the development of our sensor, a lot of effort this year went to the “Development of Type IIS cloning standard”, which allows a higher degree of modularity for NANOFLEX.
Our modelling approach is two-fold, a python based stochastic model for expression of detection proteins and a molecular dynamics pipeline for modifying the nanobody component of our sensor.
Informed decision-making is the motto of our project. From early on, we have been contacting experts and professors for their inputs. We have also organized education and collaborations programs directed to the iGEM community, but also to the general public.
We are the team of Uppsala University (Sweden) for the complicated year of 2020. With different education backgrounds and from all over the world, we are 25 students that decided to enrol in the iGEM adventure.