Humanity shares the collective responsibility to reduce the ecological footprint as much as possible. For many years we have been taking our natural resources for granted, consumption has been growing and the atmosphere has been filling up with CO2. The conversion of CO2 into products is the foundation of the bio-based economy, which has the potential to replace the use of oils. Therefore, the need for a bio-based economy has gained much interest over recent years. Right now, we see that the industry is growing and has diversified by using a variety of microorganisms to produce compounds, which we call “cell factories”.
A major problem with cell factories is the genetic instability of engineered strainsthat eventually lead to phenotypic instability. This basically means that genetic changes leading to production are not essential and cost energy for microorganisms. Over time, evolution will enter the stage and a faster-growing non-producing microorganism will outcompete the producing microorganism.