Team:SJTU-BioX-Shanghai/Implementation
LUCAS and the world
Proposed End Users
Our potential users are research groups and industries who wants to customize their proteins. We can provide them engineering proteins with specific functions and reactivities.
Envision
They can use our project in different situations where enzymes were used. For example, our directed evolved high-fidelity Cas9 can be used in in vivo gene editing therapy.
Implementation
We will work together with other labs and companies. They can give us their protein, together with the solved protein structure. We use our easy-to-use directed evolution platform and rational design program to customize their proteins.
Safety Aspects
There not too much safety problems when we mutating dCas9. We will take care of the function we are searching. For example, our directed evolved protein cannot be highly-toxic. For more details about safety, please read our safety page and safety form.
Other Challenges
It’s an extremely complicated when we analyzing the relationship between protein structure and function. With more training data, our rational design program can be more accurate, which can help our design more convincing.
SJTU-BioX-Shanghai
contact us
Contact us: sjtuigem@gmail.com or sjtuigem@gmail.com
Bio-X Institute, Shanghai Jiao Tong University, Dongchuan Rd. 800
Copyrights © 2020 SJTU-BioX-Shanghai
