Team:TJUSLS China/Attributions
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We are very grateful to those who have given us support and help along the way. It is their help that makes the project go smoothly.
Rational design
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Shuyin Wu, is responsible for the design of disulfide bonds and the design of hydrophobic interactions.
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Yanjiao Lu, determines the parameter conditions and methods for hydrogen bond construction by reading the literature.
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Guosheng Gao,reads the literature to study hydrogen bonding, proline substitution, aromatic interactions and try to modify.
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Xinyi Zhang, is responsible for the design of hydrogen bond modification based on homologous enzyme comparison by reading literature.
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Yuhan Li, looks for suitable mutation sites based on homologous enzyme alignment and b-factor screening by reading the literature.
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Yuan Wang, is responsible for the desigen of proline substitution based on b-factor screening by reading the literature.
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Xujia Liu, is responsible for the reconstruction of hydrophobic interaction based on hydrophobic interaction analysis and structural analysis by reading literature.
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Yufei Zhou, researches aromatic interactions by reading literature.
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He Zhang, is responsible for the rational design of disulfide bonds by reading literature.
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Tao Fu & Duo Zhang , is responsible for design of salt bridge based on structural analysis and homologous enzyme sequence comparison by reading literature.
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Dewu Liu, made an attempt to improve the thermal stability of PETase in terms of pocket modification.
Computationally design
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Haoyang Shi & Dewu Liu, studied and mastered the use and principle of FoldX, and helped other experimental group students learn to use FoldX.
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Haoyang Shi, is responsible for the decision-making of FoldX machine screening strategy and the analysis of data results.
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Dewu Liu, learned and installed Rosetta, and studied Rosetta principles.
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Haoyang Shi,Liu Dewu,He Zhang,Yuan Wang, performed a large number of mutation combinations.
Molecular Dynamics Simulation
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Yansong Bai and Yanjiao Lu, studied and mastered the use methods and principles of MD and made great contributions to the smooth progress of the project.
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Yansong Bai , is mainly responsible for molecular dynamics simulation and the establishment of mathematical models for data processing and prediction.
Human Practice
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Yufei Zhou, is responsible for the overall planning of the entire HP project.
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Yufei Zhou, Caroline Wang, Shuying Wu, Yuhan Li, Guosheng Gao , conducted a series of HP, including contact with enterprises, factories, government and other teams.
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Yufei Zhou and Yuhan Li , are also responsible for HP's online promotion.
Wiki&Design
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Jing Yan, is responsible for the communication between the wiki group and other groups, and is also responsible for website writing and typesetting (such as writing navigation bars, home page and detailed pages).
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Luoyan Qin , is responsible for the team's visual design, web design, poster design, etc.
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Fanghui Wang, is responsible for the design of team posters, logos, web pages and derivatives.
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Haoran Zhou , is mainly involved in the production of wiki pages, including project, modeling, and human practise related pages.
Acknowledgement
GENERAL SUPPORT
School of Life Sciences, Tianjin University Provided us with project funds，high performance computer during the whole season.
National Supercomputer Center in Tianjin
Provided us with high performance computer for MD.
PROJECT SUPPORT AND ADVICE
Professor Zefang Wang from Tianjin University, Primary PI of Our Team Gave us advice and instructions. Especially, He cheerer us up when we felt frustrated and encouraged us to overcome our limitations and keep trying for the best.
Xiaqing Zhu Graduate Student from Tianjin University, Our Instructor Provided team management advice and her experiences were extremely useful to determine our project.
Yi Wei Graduate Student from Tianjin University, Laboratory Steward Helped us with the modifying wiki and presentation, and she supervised and directed our project design.
Ruihan Dong Undergraduate Student from Tianjin University, Our Advisor, Student leader of iGEM team TJUSLS_China in 2019. Helped us with modifying wiki and her experiences helped determine our project.
Linquan Wei Undergraduate Student from Tianjin University Helped us greatly with designing and finishing wiki, who is so kind that works day and night with us.
Xiyuan Wang Undergraduate Student from Tianjin University Helped us greatly with designing and finishing wiki.
Orca Animation Studio Studio specializing in animation facture Helped us complete and improve our animated video on the home page.
Professor Cheng Zhu from Tianjin University,Our Instructor Guided us with the parameters adjustment of molecular dynamics simulation.
Lecturer Fenghui Guan from Tianjin University Guided us with the use of super computing and remote submission tasks.
Lecturer Yaxin Wang from Tianjin University Provided us with a course on COVID-9 virus during the summer camp.
tjusls_china@163.com
Address
No.92 Weijin Road,Nankai District,Tianjin,China
