Team:UPF Barcelona/Medals



1 Competition deliverables


You are actually navigating through our magnificent wiki, hope you are enjoying it!


Our poster will be presented in the virtual poster sessions which will take place over the 3 Jamboree Competition days.

Project Promotion Video

Wanting to see what is our project about in only 2 minutes? Don’t hesitate to watch our promotional video submitted in iGEM Video Universe platform. Click on the following link.

Presentation Video

If the promotional video is not enough to satisfy your curiosity on the fundamental design, functioning and implementation of Hormonic, we submitted a 20 minutes presentation video in iGEM Video Universe platform. Check it out!

Judging Form

Visit our Judging Form.

2 Attributions

Take a look at the team and attributions pages to find out what has been the master area of each of our multidisciplinary team members.

3 Project Inspiration and Description

  • The idea originated from the identification of a clear medical need and the brainstorming sessions done with our instructors and supervisors (see our Description page for further detail).
  • Hormonic represents an intein-mediated control system for thyroid homeostatic regulation.

4 Contribution

  • DIY turbidostat manual (all pdf and stl files included) as well as a detailed explanation of the calibration experiments in order to make it a robust and precise hardware system. See our Contribution page.
  • We documented several Standard Biological parts on the registry (see Parts page).


1 Engineering success

  • We followed the Engineering Design Cycle for the accomplishment of our Hormonic T3 biosensor (see Engineering page).
  • Two cycles have been successfully performed and the third one is already planned.

2 Collaborations

  • We collaborated with several iGEM teams across the world to make the synthetic biology community stronger.
  • We hosted virtual meetups, troubleshot a project as well as shared ideas with other igemers. Come and visit our Collaborations page!

3 Human Practices

  • We made sure to get advice from researchers, clinicians, associations and experts in several fields at every step of the project in order to ensure it is responsible and good for the world.
  • We documented how we incorporated their advice in Hormonic’s design and implementation. Have a look at our Human Practices page for more details.

4 Proposed Implementation

  • We analyzed and identified the potential users and beneficiaries of Hormonic final device.
  • We managed to describe in detail the final prototype of Hormonic device
  • Safety and security aspects are considered in accordance with the feedback from experts. Feel free to visit our Implementation page.


1 Integrated Human Practices

  • The influence of Human Practices over our project’s development has been key in all stages
  • Take a look at the input and output of our interviews within the Integrated Human page to see how the world has affected our project!

2 Improvement of an Existing Part

  • Experiments with both the original and the improved part (sfGFP and the incorporation of a degradation tag) were developed. Go to improve page to see the obtained results.
  • Both parts are included in the registry of iGEM.
  • To check the protocols of how the experiments were carried out check our proof of concept notebook on our experiments page!

3 Project Modelling

  • Two mathematical models were developed in order to characterize and understand the behaviour of an intein-mediated T3 biosensor and a lactone feedback system. Furthermore, these models were fitted into experimental data and sensitivity and stability analysis were performed.
  • On top of that, a model to characterize the ASV tag was designed and then, we mathematically demonstrated its ability to increase the protein degradation rate, thus reducing sensing time.
  • Come and take a look at our Modelling page!

4 Proof of Concept

  • The implementation of our lactone-mediated Proof of concept validated the capacity of a biosensor-electronic coupled approach to control homeostasis by the use of a producer and a sensor cell.
  • This Proof of concept also involved software and hardware development for the implementation of our turbidostat.
  • Feel free to explore our Proof of Concept page!

5 Science Communications

  • Our team created several ways to reach the widest range of audience as possible, and to disseminate information about synthetic biology: school engagement, live podcast sessions and PRBB open day.
  • Check our public engagement page.

6 Excellence in another area: Entrepreneurship

  • Our team made a business model for our device, and analyzed how its entrance to the market could be performed.
  • For more information about the business and financial plan don’t miss our wiki page entrepreneurship!