Besides top experts, we also interviewed common people that we’re most familiar with-our family members from all walks of life, including emergency center directors, nurses, police officers and other grass-roots staff, hoping to comprehensively understand the current situation of nosocomial infections in grassroots hospitals as well as the influenced citizen lifestyles under the pressure of coronavirus.
Nosocomial infection is so common that almost all patients in the long period of relabilitation or coma have a chance to have acquired pneumonia, and the infection is mostly mixed type. Once the infection occurs, anti-infection treatment will be very tough. Acquired pneumonia has always been a core topic in the ICU.
The pulmonary nosocomial infection has a direct connection to the use of the ventilator, which is usually used to create an artificial airway. It is done through endotracheal intubation and tracheotomy, during which there are three possible ways in which infection can occur:
In addition to the use of ventilators, there are many other factors that lead to pulmonary nosocomial infection:
At present, Pseudomonas aeruginosa ranks the top three in nosocomial infection in China. Antibiotics are included in the main therapy, but there is a certain degree of drug resistance. Therefore, these antibiotics often only play some basic roles. Combined use of antibiotics and development of new antibiotics can partly slow down the emergence of drug resistance, but combined use will also affect the function of organs such as liver and kidney. In addition to antibiotics, it is also necessary to give patients nutritional supplements to improve their immunity.
In the face of the sudden outbreak of COVID-19, front-line medical workers are faced with the difficulties of insufficient medical resources, shortage of hands and extremely high risk of infection, but they are still came to from all directions to help Wuhan. Under the epidemic situation, there were more social destablizing factors. When most people could keep themselves in quarantine at home, apart from medical workers, there were also groups of people who were going backwards regardless the threat of the disease. The control of the community, the social follow-up of migrants and vehicles, the crackdown on cases against the anti-epidemic regulations, the protection of the basic living needs of vulnerable groups, the maintenance of market order, the protection of rights and interests of citizens, etc. They stick to their positions like screws, keeping the social machine running steadily. Thanks to them, we were able to adjust to the onslaught of COVID-19 and quickly get back on track.
To obtain broad and distinct insights around the major social concerns that our project encompasses, e.g. nosocomial infection and engineered probiotic, we distributed two questionnaires with exquisitely designed questions to the community via online and offline approaches, such as social media and lecture. More than 500 answers were collected and then analyzed. We believe that the outcomes of these questionnaires not only provided us with public recognition scope of project-related themes, but pushed forward our project in different perspectives, such as inclusivity, education and entrepreneurship.
Our aim is to develop ‘integrated questionnaires’ (just like integrated human practices), which facilitate sufficient and efficient communications between us and the community. Notably, when delivering the questionnaires, we also wrote supplementary articles for education. We split the questionnaire into three sections, which include basic information, public recognition of project-related areas, and outreach questions. In Part I: Basic Information, only three necessary questions were proposed to distinguish the participants, in case that the redundancy of basic questions might lessen their willingness to accomplish our survey. In Part II, to enable quantification of participants’ understanding of ‘nosocomial infection’ and ‘engineered probiotic’, we designed a considerable proportion of numerical rating scale in our survey, instead of those ‘yes/no’ questions. Importantly, in the last section of outreach questions, several interactive questions were designed to guide the way to directly develop our project, for instance, statistical results of the ranking ‘the appropriate forms to spread relevant knowledges:’ played a decisive role in the decision-making process of our science-without-border activities.
Using the data generated from two surveys, we performed statistical analysis and those outcomes indicated the direction for us to advance. Several critical points are described whereafter:
Question 6 of engineered probiotic survey: ‘Prevent purchasing transgenic products in daily life.'
Question 15 of engineered probiotic survey: ‘Your general acceptance degree of engineered probiotics implemented in biomedical fields:’
Question 12 of nosocomial infection survey: ‘Intensive care units are germ-free.’
Question 16 of nosocomial infection survey: ‘Your general judgment towards nosocomial infections during the epidemic:’
Question 18 of nosocomial infection survey: ‘Do you think nosocomial infection-related introductions are necessary? ’
Question 19 of nosocomial infection survey: ‘Do you think these science communication activities will help improve the ongoing situations?’
Question 20 of nosocomial infection survey: ‘The appropriate forms to spread relevant knowledges:’
This cloud art created by wordart.com was derived from answers to question 19 of engineered probiotic survey, ‘In your opinion, the limiting factors that hamper the development of China bio-tech enterprises could involve:’.
In summary, we anticipate that our project will greatly benefit from the integrated questionnaires. Download PDF version of our questionnaires here:
Driven by the collaborative principles of Anti-Biofilm Community, we participated in the online campaign of #FindBiofilms, following the proposer UM_Macau. Aiming to spread the concepts of biofilms together with the detrimental impact of biofilm formation, the activity was held in different social media, such as WeChat public official account, Facebook and Instagram, for collecting daily-life pictures of biofilm-like items from diverse groups. After selection, UM_Macau displayed them in ‘A Handbook of Anti-Biofilm Community’ to fulfill education goals.