Prospects
We believe our the peptide of PTRSs, which are produced with LAE technique, are able to bind to the E protein; meanwhile, PTRSs have a huge potential on many applications. We understand that there are still many works required in order to accomplish these ideas. Here, we list the possible future directions for our project, which will be divided into two parts: environmental detection and treatment.
Environmental Detection
We envision that our kit will be expanded to detect all four serotypes of the dengue virus. Furthermore, it will also be able to identify the risk of the environments by detecting the population of mosquito vectors carrying dengue virus. We will also need to establish a score system based on our detection kit, so that we can alert the public the threat of dengue virus.
Treatment
Ultimately, we also hope our PTRSs could be involved in the treatment procedure. Ideally, PTRSs are capable to bind to the E protein of the dengue virus. Therefore, they could block the interaction between CLEC5A on a macrophage and the E protein on the virions in the blood. As the result, we could lower the possibility of severe dengue fever.
