Team:ECNUAS/Implementation
Proposed Implementation
On the basis of our experiment results, we are confident to state that the dual fluorescent reporter gene screening platform for GR anti-type 2 diabetes lead compounds does work. Thereafter, our next step should be sketching up the future application and inspiration of our platform.
1) Future application of the fluorescent reporter gene screening platform for GR anti-type 2 diabetes lead compound
With the increasing number of type 2 diabetes patients in China and abroad, it becomes more and more urgent for us to have effective drug screening tools. Even though there is still a long way from the identification of a lead compound to a new drug discovery, the more lead compounds we have, the higher possibility for us to discover effective drugs. Thus, the encouraging results of our project will add great values to future leading drug screening towards type 2 diabetes.
To be specific, it is known to the world that most pharmaceutical giants have been investing a large amount of time and capital in research and development of anti--type 2 diabetes. This fact provides us with the business niche to launch possible collaborations since our screening platform will be beneficial for the pharmaceutical giants in enhancing their research & development efficiency of anti-type 2 diabetes drugs. In this way, our project will bring business values to these respected firms and to our team in return.
In addition, if our screening platform gains success at pharmaceutical giants, (e.g. help these firms with successfully inventing new drugs towards anti-type 2 diabetes) it will finally benefit the type-2 diabetes patients, enhance their life quality and hence make a contribution to our society.
2) Inspiration for future teams’ research
The success of our project proves again the feasibility of the dual fluorescent reporter gene screening platform. Thereafter, future iGEM teams may also use this method to filter lead compounds around other possible targets or to fight against other diseases. Our experiment protocols will facilitate the progress of their coming projects.
3) Other Concerns
To support the future development of our project, it is necessary for us to distinguish our projects from other similar ones. On one hand, we may further test the feasibility of our project and keep an open-minded attitude towards our peers; on the other hand, we may also design a pitch book of our project, on the basis of which we may further enhance the popularity of our project in the society, especially among potential investors.
Pharmacology is not easy, however, we consider that adherence to it with righteous attitude, confidence and professionalism, just like what we have enjoyed in our this year’s project, we will in the end add certain values to this area with leading knowledge and techniques, such as synthetic biology.
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