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<link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/fonts.css&action=raw&ctype=text/css" /> | <link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/fonts.css&action=raw&ctype=text/css" /> | ||
<link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/index.css&action=raw&ctype=text/css" /> | <link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/index.css&action=raw&ctype=text/css" /> | ||
+ | <link rel="stylesheet" type="text/css" href="https://2020.igem.org/wiki/index.php?title=Template:Vilnius-Lithuania/CSS/Animations&action=raw&ctype=text/css" /> | ||
</head> | </head> | ||
<body> | <body> | ||
<section class="container" id="intro-page"> | <section class="container" id="intro-page"> | ||
− | + | <div id="intro-header"> | |
− | + | <svg id="waves" width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
<path id="wave0" d="" fill="#fafafc" waveHeight="360" waveDelta="30" speed="0.2" wavePoints="8" /> | <path id="wave0" d="" fill="#fafafc" waveHeight="360" waveDelta="30" speed="0.2" wavePoints="8" /> | ||
<path id="wave1" d="" fill="#679BF4" waveHeight="330" waveDelta="36" speed="0.11" wavePoints="6" /> | <path id="wave1" d="" fill="#679BF4" waveHeight="330" waveDelta="36" speed="0.11" wavePoints="6" /> | ||
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<path id="wave7" d="" fill="#121212" waveHeight="150" waveDelta="28" speed="0.28" wavePoints="7" /> | <path id="wave7" d="" fill="#121212" waveHeight="150" waveDelta="28" speed="0.28" wavePoints="7" /> | ||
</svg> | </svg> | ||
− | + | </div> | |
− | + | <div id="intro"> | |
− | + | <div id="text-wrapper"> | |
− | + | <div id="title" class="elevate-navbar"> | |
− | + | <h1>flavoflow</h1> | |
− | + | </div> | |
− | + | <div id="desc-wrapper"> | |
− | + | <div id="center-desc" style="width: -webkit-fit-content;"> | |
− | + | <span id="description"></span> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | </section> | |
− | + | <main id="storytelling"> | |
− | + | <div class="black-bg big-section"> | |
− | + | <div id="firstpart" class="section centered"> | |
− | + | <div id="fish-icon" class="centered icon white"> | |
− | + | <p class="black center">Throughout history <b>fish</b> have always been one of the most <b>important food sources.</b></p> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="secondpart" class="section centered"> | |
− | + | <div class="centered wdt-60"> | |
− | + | <p class="white center">The consumption of aquaculture products has been steadily increasing during the past <b>50 years</b> and has now <b>doubled</b> since.</p> | |
− | + | </div> | |
− | + | <div class="icon dark"></div> | |
− | + | </div> | |
− | + | <div id="thirdpart" class="section centered two-parts"> | |
− | + | <div class="half"> | |
− | + | <p class="white">Growing fish consumption drives a need for a more <b>intensive fish farming</b> - a need which emerging aquaculture farms have stepped in to satisfy.</p> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <div class="icon dark"></div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="fourthpart" class="section centered two-parts"> | |
− | + | <div class="half"> | |
− | + | <p class="white">In order to obtain greater amounts of fish in a shorter period of time, aquafarms have implemented <b>recirculating aquaculture systems</b> (RAS).</p> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <div class="icon dark"></div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="fifthpart" class="section two-parts"> | |
− | + | <div class="half"> | |
− | + | <h2 class="white">Advantages of RAS</h2> | |
− | + | <div class="list"> | |
− | + | <div class="list-item"> | |
− | + | <div></div> | |
− | + | <p>reduced water and land needs</p> | |
− | + | </div> | |
− | + | <div class="list-item"> | |
− | + | <div></div> | |
− | + | <p>fully controlled environment</p> | |
− | + | </div> | |
− | + | <div class="list-item"> | |
− | + | <div></div> | |
− | + | <p>automated feeding strategy</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <h2 class="white">Disadvantages of RAS</h2> | |
− | + | <div class="list"> | |
− | + | <div class="list-item"> | |
− | + | <div></div> | |
− | + | <p>high electricity consumption</p> | |
− | + | </div> | |
− | + | <div class="list-item"> | |
− | + | <div></div> | |
− | + | <p>water quality</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="sixthpart" class="section centered"> | |
− | + | <div class="centered"> | |
− | + | <h1>However, the biggest challenge is</p> | |
− | + | </div> | |
− | + | <div class="icon dark"></div> | |
− | + | </div> | |
− | + | <div id="seventhpart" class="section centered two-parts"> | |
− | + | <div class="half"> | |
− | + | <p class="white">Since the water in RAS is circulated between tanks, if <b>one bacteria-infected fish</b> enters the system, not long after, the entire RAS system can become <b>contaminated</b>.</p> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <div class="icon dark"></div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="milkWave"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
<path class="animWavePath" d="" fill="#fafafc" /> | <path class="animWavePath" d="" fill="#fafafc" /> | ||
</svg> | </svg> | ||
− | + | </div> | |
− | + | </div> | |
− | + | <div class="white-bg big-section"> | |
− | + | <div class="section centered wdt-60"> | |
− | + | <div> | |
− | + | <p class="black center">Diseases caused by Flavobacterium spp. constitute one of the <b>biggest host</b> and geographic ranges of the <b>bacterial fish pathogens</b>.</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="bact" class="section centered"> | |
− | + | <div> | |
− | + | <p class="black center">The<b> most common</b> of these bacteria are the two opportunistic species:</p> | |
− | + | </div> | |
− | + | <div class="row"> | |
− | + | <div class="half"> | |
− | + | <p class="black center">Flavobacterium<br>psychrophilum</p> | |
− | + | <p class="yellow center"><b>causes bacterial coldwater disease</b></p> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <p class="black center">Flavobacterium<br>columnare</p> | |
− | + | <p class="yellow center"><b>causes columnaris disease</b></p> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="black-bg big-section"> | |
− | + | <div class="milkWave rotate-wave"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
<path class="animWavePath" d="" fill="#fafafc" /> | <path class="animWavePath" d="" fill="#fafafc" /> | ||
</svg> | </svg> | ||
− | + | </div> | |
− | + | <div class="section centered two-parts"> | |
− | + | <div class="centered"> | |
− | + | <h1>What's the deal with the fish?</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div id="fish-symptoms" class="section centered wdt-80 two-parts"> | |
− | + | <div class="half"> | |
− | + | <p class="white">Typically, these diseases are denoted by heavy bacterial colonizations of gill epithelium and eroded fin tips.</p> | |
− | + | <p class="white">However, after these physical changes are being seen, the respiratory and osmoregulatory functions are already damaged.</p> | |
− | + | <p class="white">Thus, if the disease is not detected in a span of a few days, it can result in massive fish die-offs.</p> | |
− | + | </div> | |
− | + | <div class="half"> | |
− | + | <div class="icon dark" id="fishIcon"></div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="section centered"> | |
− | + | <div class="centered"> | |
− | + | <h2 class="white">Are there any solutions to this problem?</h2> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="milkWave"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
<path class="animWavePath" d="" fill="#fafafc" /> | <path class="animWavePath" d="" fill="#fafafc" /> | ||
</svg> | </svg> | ||
− | + | </div> | |
− | + | </div> | |
− | + | <div class="white-bg big-section"> | |
− | + | <div class="section centered"> | |
− | + | <div class="centered"> | |
− | + | <h1 class="black center">Actually, yes!</h1> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="section centered wdt-60"> | |
− | + | <div> | |
− | + | <p class="black center">We have found <b>three</b> major approaches to solving the Flavoproblem.</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="white-bg big-section smallWaves"> | |
− | + | <div class="milkWave small"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
− | + | <path class="animWavePath" d="" fill="#DDE4FD" /> | |
− | + | </svg> | |
− | + | </div> | |
− | + | <div class="milkWave small" style="top: 20px;"> | |
− | + | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | |
− | + | <path class="animWavePath " d=" " fill="#B8C7FC " /> | |
− | + | </svg> | |
− | + | </div> | |
+ | <div class="milkWave small" style="top: 40px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#8BA2F7 " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 60px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#6281ef " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="lightblue-bg big-section"> | ||
+ | <div class="section centered "> | ||
+ | <div class="centered "> | ||
+ | <h1 class="white title ">detection</h1> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="section centered wd-50 "> | ||
+ | <div> | ||
+ | <p class="white ">One of our main goals is the development of a rapid detection test is based on helicase-dependent amplification (HDA) and lateral-flow assay (LFA) methods. This kit will help farmers in identifying what the Flavo is in their tanks.</p> | ||
+ | </div> | ||
+ | </div> | ||
− | + | <div class="section centered wd-50 "> | |
− | + | <div> | |
− | + | <p class="white ">Detection, however, is only a tool which will reduce aquafarm’s losses - it will not solve the underlying problem.</p> | |
− | </div> | + | </div> |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="lightblue-bg big-section smallWaves"> | |
− | + | <div class="milkWave small"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
− | + | <path class="animWavePath" d="" fill="#4E71EB" /> | |
− | + | </svg> | |
− | + | </div> | |
− | + | <div class="milkWave small" style="top: 20px;"> | |
− | + | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | |
− | + | <path class="animWavePath " d=" " fill="#3C62E3 " /> | |
− | + | </svg> | |
− | + | </div> | |
− | + | <div class="milkWave small" style="top: 40px;"> | |
− | + | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | |
− | + | <path class="animWavePath " d=" " fill="#365AD8 " /> | |
− | </div> | + | </svg> |
− | + | </div> | |
− | + | <div class="milkWave small" style="top: 60px;"> | |
− | + | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | |
− | + | <path class="animWavePath " d=" " fill="#3356CE " /> | |
− | + | </svg> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="brightblue-bg big-section "> | |
− | + | <div class="section centered "> | |
− | + | <div class="centered "> | |
− | + | <h1 class="white title ">treatment</h1> | |
− | </div> | + | </div> |
− | + | </div> | |
− | + | <div class="section centered wd-50 "> | |
− | + | <div> | |
− | + | <p class="white ">Due to this reason, we have developed a new fundamental method to treat these diseases based on toxin-antitoxin or exolysin-endolysin systems. </p> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="section centered wd-50 "> | |
− | + | <div> | |
− | + | <p class="white ">On the other hand, no matter how perfect the treatment strategy is, it solves only the consequences of the disease.</p> | |
− | + | </div> | |
− | + | </div> | |
− | + | </div> | |
− | + | <div class="brightblue-bg big-section smallWaves"> | |
− | + | <div class="milkWave small"> | |
− | + | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | |
− | + | <path class="animWavePath" d="" fill="#2B4FC9" /> | |
− | + | </svg> | |
− | + | </div> | |
− | + | <div class="milkWave small" style="top: 20px;"> | |
− | + | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | |
− | + | <path class="animWavePath " d=" " fill="#264AC6 " /> | |
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 40px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#103BAD " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 60px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#11348F " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="darkblue-bg big-section "> | ||
+ | <div class="section centered "> | ||
+ | <div class="centered "> | ||
+ | <h1 class="white title ">prevention</h1> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="section centered wd-50 "> | ||
+ | <div> | ||
+ | <p class="white ">Keeping this in mind, we have also created an innovative prevention tool, which is based on the packaging of immunogenic proteins into alginate beads. </p> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="darkblue-bg big-section smallWaves"> | ||
+ | <div class="milkWave small"> | ||
+ | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | ||
+ | <path class="animWavePath" d="" fill="#142455" /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 20px;"> | ||
+ | <svg width="100%" height="100%" version="1.1" xmlns="http://www.w3.org/2000/svg"> | ||
+ | <path class="animWavePath" d="" fill="#131F43" /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 40px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#0F162C " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | <div class="milkWave small" style="top: 60px;"> | ||
+ | <svg width="100%" height="100%" version="1.1 " xmlns="http://www.w3.org/2000/svg "> | ||
+ | <path class="animWavePath " d=" " fill="#121212 " /> | ||
+ | </svg> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div id="links " class="black-bg big-section "> | ||
+ | <div class="section centered "> | ||
+ | <div class="centered "> | ||
+ | <h1 class="white title ">let's dive in</h1> | ||
+ | </div> | ||
+ | </div> | ||
+ | <div class="section centered nf "> | ||
+ | <div class="row "> | ||
+ | <div class="icon dark "></div> | ||
+ | <div class="icon dark "></div> | ||
+ | <div class="icon dark "></div> | ||
+ | </div> | ||
+ | <div class="row "> | ||
+ | <div class="icon dark "></div> | ||
+ | <div class="icon dark "></div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </div> | ||
+ | </main> | ||
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Revision as of 12:04, 6 October 2020
Throughout history fish have always been one of the most important food sources.
The consumption of aquaculture products has been steadily increasing during the past 50 years and has now doubled since.
Growing fish consumption drives a need for a more intensive fish farming - a need which emerging aquaculture farms have stepped in to satisfy.
In order to obtain greater amounts of fish in a shorter period of time, aquafarms have implemented recirculating aquaculture systems (RAS).
Advantages of RAS
reduced water and land needs
fully controlled environment
automated feeding strategy
Disadvantages of RAS
high electricity consumption
water quality
However, the biggest challenge is
Since the water in RAS is circulated between tanks, if one bacteria-infected fish enters the system, not long after, the entire RAS system can become contaminated.
Diseases caused by Flavobacterium spp. constitute one of the biggest host and geographic ranges of the bacterial fish pathogens.
The most common of these bacteria are the two opportunistic species:
Flavobacterium
psychrophilum
causes bacterial coldwater disease
Flavobacterium
columnare
causes columnaris disease
What's the deal with the fish?
Typically, these diseases are denoted by heavy bacterial colonizations of gill epithelium and eroded fin tips.
However, after these physical changes are being seen, the respiratory and osmoregulatory functions are already damaged.
Thus, if the disease is not detected in a span of a few days, it can result in massive fish die-offs.
Are there any solutions to this problem?
Actually, yes!
We have found three major approaches to solving the Flavoproblem.
detection
One of our main goals is the development of a rapid detection test is based on helicase-dependent amplification (HDA) and lateral-flow assay (LFA) methods. This kit will help farmers in identifying what the Flavo is in their tanks.
Detection, however, is only a tool which will reduce aquafarm’s losses - it will not solve the underlying problem.
treatment
Due to this reason, we have developed a new fundamental method to treat these diseases based on toxin-antitoxin or exolysin-endolysin systems.
On the other hand, no matter how perfect the treatment strategy is, it solves only the consequences of the disease.
prevention
Keeping this in mind, we have also created an innovative prevention tool, which is based on the packaging of immunogenic proteins into alginate beads.
let's dive in