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Once the mechanism of our detection technique was designed, we performed laboratory experiments to determine the experimental conditions of the new technology. After a few rounds of optimization, a proof-of-concept experiment showed how the reactions of the technology can be successfully connected to detect, amplify and report the presence of a target DNA. On this page, we show the experiments that led to the proof-of-concept in detail. The results were also published as a pre-print on BioRxiv; the complete publication can be viewed after the Discussion section.

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We are the 2020 team of iGEM Leiden. With an interdisciplinary team of students we aim to develop a point-of-care rapid diagnostic tool for infectious diseases!

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iGEM Team Leiden
Sylviusweg 72, 2333BE Leiden