Difference between revisions of "Team:Calgary/Description"

Line 59: Line 59:
  
 
       }
 
       }
 +
 +
@media (max-width: 767px) {
 +
 +
.banner-image {
 +
  background-position: center;
 +
}
 +
}
  
 
   </style>
 
   </style>

Revision as of 15:48, 25 October 2020



THE OVIITA PHILOSOPHY

In 1990, the World Summit for Children called for the ‘virtual elimination of Vitamin A deficiency and its consequences, including blindness” (1)

Our overall goals for Oviita and it's implementation are that it is:

  • practical and simple to maintain within communities
  • promote self-sufficiency and autonomy
  • address the concerns voiced by the end users

VITAMIN A DEFICIENCY

Vitamin A is typically taken up in the diet from specific plant and animal sources. Without these sources, deficiency compromises the immune system, stunts growth, and blinds the eyes, leaving patients vulnerable.


Vitamin A deficiency (VAD) is one of the leading causes of preventable childhood mortality. Vitamin A is acquired from specific plant and animal sources in our diet. Without these sources, the resulting deficiency can lead to destruction of the immune system, stunted growth, and blindness, leaving patients vulnerable to infection and mortality.


VAD disproportionately harms some of the world’s most vulnerable populations, particularly pregnant women and children who lack access to varied diets due to socioeconomic and cultural factors. It is widespread in regions of Africa and South Asia where diets may contain low amounts of Vitamin A. Furthermore, since vitamin A is fat soluble, deficiency can also be exacerbated by a lack of dietary fat, which is common in many of the same regions.

Change to map graphic


Current solutions exist which have helped significantly, such as Vitamin A supplementation through annual shots and fortification of food. However, these solutions can leave communities reliant on charity or government aid infrastructure to provide them with ongoing, recurring relief. As a result, these solutions are unsustainable, and vulnerable in case of failure of infrastructure or continued funding. They also fail to address lipid deficiency.

Figure 2.

Vitamin A is typically taken up in the diet from specific plant and animal sources. Without these sources, deficiency compromises the immune system, stunts growth, and blinds the eyes, leaving patients vulnerable.

One of the biggest causes of preventable childhood mortality, Vitamin A Deficiency, currently afflicts an estimated 250 million women and children worldwide.



VAD disproportionately harms some of the world’s most vulnerable populations. It is widespread in regions of Africa and South Asia, where diets contain low amounts of Vitamin A, and is further exacerbated by a lack of dietary fat.

OUR APPROACH

Engineering Cellulases involves something something, it's cool and we love to do it. A main part of our project.

Biocontainment is an aspect of our project that is also very important to what we're doing.

Implementation involves many aspects such as building a bioreactor, doing some other stuff, and one last one. One of the last most important aspects of our project.

When it came to selecting our choice of yeast chassis, we had six major considerations.

After the careful consideration of many organisms, we selected Y. lipolytica OBJMY3501. As a strain of the well-characterized yeast, Y, lipolytica, OBJMY3501 has already been engineered for beta carotene production and satisfies all of our criteria.