18desilvni (Talk | contribs) |
18desilvni (Talk | contribs) |
||
Line 10: | Line 10: | ||
/> | /> | ||
</head> | </head> | ||
− | <body style="background-color: #ffffff; overflow-x: hidden"> | + | <body style="background-color: #ffffff; overflow-x: hidden; height:100vh;"> |
<div class="main"> | <div class="main"> | ||
<div class="container-fluid"> | <div class="container-fluid"> |
Revision as of 16:14, 23 October 2020
A MAJOR PROBLEM
VITAMIN A DEFICIENCY IS A LEADING CAUSE OF CHILDHOOD MORTALITY
AND BLINDNESS.
WE'RE HERE TO CHANGE THAT.
OVIITA DESIGN
As a leading global cause of preventable blindness and mortality, vitamin A deficiency (VAD) is a serious health problem, particularly in developing regions. Oviita aims to equip these vulnerable regions with a sustainable and community-based solution to VAD. Our solution uses a food-safe strain of Yarrowia lipolytica modified to produce beta-carotene, a Vitamin A precursor. By engineering this yeast to produce cellulase, VAD communities can grow it as their own vitamin A supplement using readily-available plant matter as feedstock. To facilitate community integration, we designed bioreactor schematics based on locally-available resources, and made the yeast auxotrophic to ensure safe growth with no environmental risk. We also created a Vitamin A biosensor to improve VAD testing, and included an anthelmintic agent in the yeast to combat poor intestinal health, two contributing factors to VAD. Through these solutions, Oviita aims to be a sustainable and community-based adjunct to global efforts against VAD.